Enlarging the volume of subcutaneous autoinjections

In ONdrug Delivery magazine’s October issue on Pre-filled Syringes and Injection Devices, SHL Medical’s Gary Calderwood, Raluca Ganea, and Gene Rhode Fuensalida Pantig talk about the evolving trends in subcutaneous delivery of parenteral formulations, most recently including larger administration volumes.

Here, the authors review how the parenteral space has transformed within just the past decade and report how SHL’s portfolio of autoinjector technologies has evolved to deliver subcutaneous parenteral drugs of varying formulations, including the growing need for larger administration volumes. To respond to this growing need, SHL launched the Maggie 5.0 mL autoinjector in May 2022. Based on the market-proven Needle Isolation Technology (NIT®), the Maggie 5.0 mL device eliminates the need for users to manually attach the needle prior to injection, and allows for full control and customization of the pre-attached cannula. With NIT, users simply unscrew the cap to engage the needle with the cartridge, thereby seamlessly and intuitively opening the fluid path at the point of use. This cannula technology enables the autoinjector to accommodate a wide variety of formulation characteristics, such as: large volumes, high viscosities, lyophilized and suspension drugs, as well as supporting formulations sensitive to contact with steel and air.

Access the article here to learn more about SHL’s recently expanded drug delivery solutions that address varying formulation requirements, as well as pharma and patient needs.